Table II.

Rates of adverse events occurring within 72 hours after LAIV administration in this study compared with published rates in the literature

Symptoms within 72 h	Current study		Reported
Allergic reaction (mild symptoms) only	9/433	2.1%	0.02%
Allergic reaction: anaphylaxis	0/433	0%	0%
Fever	25/426	5.9%	5.4%
Nasal symptoms	65/426	15.3%	31%
Wheeze (parent reported)	13/426	3.1%	Not reported
Wheeze requiring treatment by physician	0/426	0%	0.2%
Lower respiratory symptoms	26/426	6.1%	Not reported
Eczema flare	13/426	3.1%	Not reported

Rates are reported as a proportion of the total number of doses given to be consistent with the method of reporting used in the existing literature.¹⁰