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. 2015 Aug 14;6:46. doi: 10.1186/s13229-015-0040-1

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© Mor et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — miR-21-5p expression correlates with less OXTR protein translation from mRNA in the brain. a Western blot analysis of OXTR in the human brain samples. Hsc70 is the endogenous control. b Quantitative analysis of relative OXTR protein levels in control and autism groups. OXTR levels were normalized to Hsc70, and data is presented as relative quantity. p = 0.089 two-tailed t test. c, d Spearman’s correlation coefficient and respective p value between miR-21-5p (c) and miR-451a (d) expression and the OXTR protein/mRNA ratio in each individual. a.u. signifies arbitrary units. There is a significant negative correlation between miR-21-5p expression and OXTR protein/mRNA ratio in human brain samples