Table 5.
SBA geometric mean titres at baseline and 4 weeks after 2 or 3 doses of MenPF-1 (95% CI).
| Strain | SBA GMTs (95% CI) |
|||||
|---|---|---|---|---|---|---|
| 25 μg dose |
50 μg dose |
|||||
| Baseline | After 2 doses | After 3 doses | Baseline | After 2 doses | After 3 doses | |
| 44/76 WT | 4.8 (2.9, 7.9) | 17.0 (9.2, 31.5) | 24.1 (12.3, 47.3) | 3.5 (2.4, 5.0) | 23.0 (12.1, 43.8) | 31.1 (19.2, 50.5) |
| 44/76 FetAonPorAon | 6.3 (3.7, 10.7) | 21.2 (12.1, 37.4) | 30.0 (15.7, 57.5) | 2.2 (2.8, 6.4) | 42.7 (23.1, 79.1) | 49.9 (29.8, 83.5) |
| 44/76 FetAoffPorAon | 4.2 (2.6, 6.8) | 14.6 (7.7, 27.6) | 19.9 (9.9, 40.1) | 3.0 (2.3, 4.0) | 26.1 (12.8, 53.4) | 29.4 (16.4, 52.9) |
| 44/76 FetAoffPorAoff | 3.2 (2.3, 4.6) | 4.3 (2.8, 6.4) | 3.6 (2.5, 5.4) | 2.5 (2.2, 2.9) | 4.8 (3.0, 7.8) | 6.6 (3.6, 11.9) |
| 44/76 FetAonPorAoff | 4.5 (2.7, 7.6) | 4.7 (3.0, 7.3) | 7.3 (4.6, 11.6) | 3.1 (2.3, 4.3) | 7.6 (4.4, 12.9) | 11.2 (6.5, 19.2) |