Fig. 4.

DZNep with Daunoblastine in Jurkat cell growth inhibition. DZNep and Daunoblastine have a synergistic effect on Jurkat cell growth inhibition. We have evaluated the growth inhibition induced by different concentrations of DZNep and Daunoblastine at 48 (a) and 72 h (b). We have performed these experiments with MTT assay and the resulting data were elaborated with the dedicated software Calcusyn as described in “Materials and Methods” section. In the figure, it is shown the isobologram analysis of the effects on growth inhibition of DZNep and Daunoblastine combinations, used (25:50) concentrations. CI, combination index. Each point is the mean of at least four different replicate experiments