Table 1.
Feature | Delirium | Dementia |
---|---|---|
Onset | Abrupt, though initial loss of mental clarity may be subtle | Insidious and progressive |
Duration | Hours to days (though can be prolonged) | Months to years |
Attention | Reduced ability to focus, sustain, or shift attention is a hallmark feature, occurring early in presentation | Normal unless severe dementia |
Consciousness (awareness of the environment) | Fluctuating (making assessment at multiple timepoints necessary), reduced level of consciousness and impaired orientation | Generally intact |
Speech | Incoherent, disorganised; distractible in conversation | Ordered, may develop anomia or aphasia |
Other features | Caused by underlying medical condition, substance intoxication, or medication side effect; Hyperactive, hypoactive, and mixed forms of psychomotor disturbance are possible; disruption in sleep duration and architecture; perceptual disturbances | Caused by underlying neurological process (e.g. beta-amyloid plaque accumulation in Alzheimer’s disease), with symptoms varying depending on underlying pathologies (e.g. fluctuations in cognition are a feature of Lewy body dementia) |
Note that there is substantial overlap between these syndromes; they may coexist in an individual patient.