Skip to main content
. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: Lancet Neurol. 2015 Jun 29;14(8):823–832. doi: 10.1016/S1474-4422(15)00101-5

Table 1.

Comparative features of delirium and dementia

Feature Delirium Dementia
Onset Abrupt, though initial loss of mental clarity may be subtle Insidious and progressive
Duration Hours to days (though can be prolonged) Months to years
Attention Reduced ability to focus, sustain, or shift attention is a hallmark feature, occurring early in presentation Normal unless severe dementia
Consciousness (awareness of the environment) Fluctuating (making assessment at multiple timepoints necessary), reduced level of consciousness and impaired orientation Generally intact
Speech Incoherent, disorganised; distractible in conversation Ordered, may develop anomia or aphasia
Other features Caused by underlying medical condition, substance intoxication, or medication side effect; Hyperactive, hypoactive, and mixed forms of psychomotor disturbance are possible; disruption in sleep duration and architecture; perceptual disturbances Caused by underlying neurological process (e.g. beta-amyloid plaque accumulation in Alzheimer’s disease), with symptoms varying depending on underlying pathologies (e.g. fluctuations in cognition are a feature of Lewy body dementia)

Note that there is substantial overlap between these syndromes; they may coexist in an individual patient.