Table 2.
Parameters | T2DM | T2DM + CAD | P value |
---|---|---|---|
Triglycerides (mmol/L) | 1.72 ± 0.78 | 1.91 ± 0.81 | NS |
Cholesterol (mmol/L) | |||
Total | 4.99 ± 0.93 | 5.63 ± 1.24 | <0.001 |
LDL | 3.20 ± 0.85 | 3.80 ± 1.13 | <0.001 |
HDL | 1.06 ± 0.23 | 0.98 ± 0.20 | NS |
Non-HDL | 3.90 ± 0.95 | 4.65 ± 1.18 | 0.01 |
Unesterified cholesterol | 0.85 ± 0.15 | 0.93 ± 0.20 | 0.02 |
Triglycerides/HDL-cholesterol | 8.5 ± 5.1 | 10.4 ± 7.3 | NS |
Apolipoproteins (mg/dL) | |||
A-I | 139.3 ± 28.1 | 132.5 ± 24.3 | NS |
B | 96.0 ± 19.5 | 103.1 ± 20.4 | 0.03 |
LDL cholesterol/apo B | 1.34 ± 0.29 | 1.23 ± 0.57 | NS |
NEFA (g/L) | 0.13 ± 0.06 | 0.11 ± 0.05 | NS |
Total/unesterified cholesterol | 5.8 ± 1.0 | 6.2 ± 1.2 | 0.05 |
CETP (µg/mL) | 2.5 ± 1.1 | 2.1 ± 1.0 | 0.02 |
CETP activity (pmol/µL/h) | 68.4 ± 15.6 | 70.4 ± 12.5 | NS |
LCAT activity | 1.33 ± 0.10 | 1.34 ± 0.12 | NS |
Data are expressed as mean ± SD.
NS nonstatistically significant, HDL high density lipoprotein, LDL low density lipoprotein, NEFA non-esterified fatty acids, CETP cholesteryl ester transfer protein, LCAT lecithin-cholesterol acyltransferase, LCAT activity is expressed by the hydrolyzed monomer ratio 390/470 nm.