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. 2015 Aug 10;6:7912. doi: 10.1038/ncomms8912

Figure 8. Mtb ΔglpXΔgpm2 is attenuated in vivo.

Figure 8

(a) Lung c.f.u. from C57BL/6 mice infected with WT Mtb (black), ΔglpX (red), ΔglpXΔgpm2 (orange) and complemented strains ΔglpXΔgpm2/C (glpX) (purple) and ΔglpXΔgpm2/C (gpm2) (blue). ND indicates no detectable c.f.u. burden for ΔglpXΔgpm2 at day 56. Data represent the mean±s.d. of four mice per time point. Dashed line indicates limit of detection of 4 c.f.u. per lung. (b) Spleen c.f.u. from C57BL/6 mice infected with WT Mtb (black), ΔglpX (red), ΔglpXΔgpm2 (orange) and complemented strains ΔglpXΔgpm2/C (glpX) (purple) and ΔglpXΔgpm2/C (gpm2) (blue). ND indicates no detectable c.f.u. burden for ΔglpXΔgpm2 at day 28 and day 56. Data represent the mean±s.d. of four mice per time point. Dashed line indicates limit of detection of 4 c.f.u. per spleen.