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. 2015 Jul 17;73(7):ftv047. doi: 10.1093/femspd/ftv047

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© FEMS 2015.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Comparative genomics for CS8 and CS8B from this study. Comparative genomics with CS8B cof operon from this study at the bottom and CS8 of accession AB049751 at the top using GenomeMatcher (Ohtsubo et al. 2008). cofR, cofS, cofT, cofB, cofC, cofD, cofE, cofF, cofG, cofH and cofI remain conserved with more than 96% similarity upstream. CFA/III gene products are cofA- major pilin, cofB- minor pilin, cofD- secretin, cofE, cofF and cofG- IMAPs (inner membrane accessory proteins), cofH- assembly ATPase, cofI- IMCP (inner membrane core protein), cofJ- secreted colonization factor, cofP- prepilin peptidase. Comparing CS8B cof operon to CS8 reveals divergence in cofA, cofP and cofJ, which encode the major subunit pilin, the prepilin peptidase and the secreted colonization factor, respectively. Colored scale on the right-hand side indicates percent nucleotide identity. Off-white areas between cofA, cofJ and cofP represent regions of no synteny.