Table 3.
Variable | Radical surgery group (n = 112) | Standard surgery group (n = 241) | P value* |
---|---|---|---|
Residual disease, in overall | <0.001 | ||
0 cm | 46 (41.1 %) | 0 (0 %) | |
0.1–0.5 cm | 46 (41.1 %) | 27 (11.2 %) | |
0.5–1 cm | 15 (13.4 %) | 78 (32.4 %) | |
>1 cm | 5 (4.5 %) | 136 (56.4 %) | |
Residual disease in upper abdomen | <0.001 | ||
0 cm | 76(67.9 %) | 0(0 %) | |
0.1–0.5 cm | 24(21.4 %) | 30(12.4 %) | |
0.5–1 cm | 10(8.9 %) | 75(31.1 %) | |
>1 cm | 2(1.8 %) | 136(56.4 %) | |
Estimated blood loss | <0.001 | ||
Median volume | 800 ml | 600 ml | |
(range) | (100–4000) | (100–3000) | |
Intraoperative blood transfusion | <0.001 | ||
Median volume | 800 ml | 400 ml | |
(range) | (0–3200) | (0–2400) | |
Operative time | <0.001 | ||
Median | 171 min | 124 min | |
(range) | (75–360) | (51–318) | |
ICU stay | 0.018 | ||
Yes | 28 (25.0 %) | 35 (14.5 %) | |
No | 84 (75.0 %) | 206 (85.5 %) | |
Length of hospitalization | <0.001 | ||
Mean | 19.96 days | 10.39 days | |
(range) | (4–190)b | (4–42) |
*Tested by Chi-square or Mann–Whitney U.b33 patients (29.5 %) in radical surgery group participated in a phase II clinical trial on intraperitoneal chemotherapy and were assigned to receive IP chemotherapy for 4 cycles weekly post operative in hospital, whereas only 7 patients (1.7 %) in standard surgery group participated in this trial and received IP chemotherapy. One patient stayed in hospital for 190 days because she received all the cycles of IP and IV chemotherapy in hospital