Table 2.
Sample n = 170 (82 Males) | DRD2 rs1076560 GG Subjects n = 116 (57 Males) | DRD2 rs1076560 T Carriers n = 54 (1 TT) (25 Males) | Cannabis-Naïve Subjects n = 103 (50 Males) | Cannabis Users n = 67 (32 Males) | |
---|---|---|---|---|---|
Age (M ± SD) | 28.36 (8.23) | 28.41 (8.29) | 28.26 (8.18) | 28.63 (8.64) | 27.94 (7.60) |
Range | 19–51 | 19–51 | 19–49 | 19–51 | 19–50 |
Distribution | n (%) | n (%) | n (%) | n (%) | n (%) |
18–29 | 134 (78.8) | 91 (78.5) | 43 (79.6) | 82 (79.6) | 52 (77.6) |
30–39 | 24 (14.1) | 16 (13.8) | 8 (14.8) | 14 (13.6) | 10 (14.9) |
40–49 | 10 (5.9) | 7 (6) | 3 (5.6) | 6 (5.8) | 4 (6) |
50–59 | 2 (1.2) | 2 (1.7) | 0 | 1 (1) | 1 (1.5) |
60–65 | — | — | — | — | — |
M (SD) | M (SD) | M (SD) | M (SD) | M (SD) | |
PSES | 42.65 (16.97) | 43.01 (16.94) | 41.67 (17.21) | 42.80 (17.40) | 42.42 (16.40) |
Handedness | 0.84 (0.26) | 0.84 (0.26) | 0.83 (0.27) | 0.84 (0.27) | 0.83 (0.27) |
IQ | 107.52 (11.78) | 107.74 (11.41) | 107.09 (12.72) | 107.50 (11.32) | 107.55 (12.72) |
n (%) | n (%) | n (%) | n (%) | n (%) | |
Tobacco use | |||||
ND yes | 52 (41.9) | 34 (40.5) | 18 (45) | 27 (36.5) | 25 (50) |
ND no | 72 (58.1) | 50 (59.5) | 22 (55) | 47 (63.5) | 25 (50) |
No details | 46 | 32 | 14 | 29 | 17 |
Alcohol use | |||||
HD yes | 57 (46) | 38 (45.2) | 19 (47.5) | 33 (44.6) | 24 (48) |
HD no | 67 (54) | 46 (54.8) | 21 (52.5) | 41 (55.4) | 26 (52) |
No details | 46 | 32 | 14 | 29 | 17 |
Cannabis use | |||||
Yes | 67 (39.4) | 46 (39.7) | 21 (38.9) | ||
Never | 103 (60.6) | 70 (60.3) | 33 (61.1) | ||
Dailya | 8 (11.9) | 5 (10.9) | 3 (14.3) | ||
Weekly or lessa | 59 (88.1) | 41 (89.1) | 18 (85.7) |
Note: HD, harmful drinking; IQ, Intelligence Quotient; ND, nicotine dependence; PSES, parental socioeconomical status.
aIn those who had ever used cannabis; there were no significant differences between GG subjects and T carrying subjects as well as between cannabis users and cannabis-naïve subjects among demographic measures and substance use (all P > .1).