Table 3.
Description of the Sample for the Cognitive Performance Evaluation
| Sample n = 221 (120 Males) |
DRD2 rs1076560 GG Subjects n =173 (93 Males) | DRD2 rs1076560 T Carriers n = 48 (3 TT) (27 Males) | Cannabis-Naïve Subjects n = 126 (67 Males) | Cannabis Users n = 95 (53 Males) | |
|---|---|---|---|---|---|
| Age (M ± SD) | 27.40 (7.69) | 27.31 (7.70) | 27.75 (7.71) | 27.23 (7.46) | 27.63 (8.02) |
| Range | 18–63 | 18–63 | 18–58 | 18–58 | 18–63 |
| Distribution | n (%) | n (%) | n (%) | n (%) | n (%) |
| 18–29 | 173 (78.3) | 137 (79.2) | 36 (75) | 99 (78.6) | 74 (77.9) |
| 30–39 | 29 (13.1) | 21 (12.1) | 8 (16.7) | 17 (13.5) | 12 (12.6) |
| 40–49 | 14 (6.3) | 11 (6.4) | 3 (6.2) | 7 (5.5) | 7 (7.5) |
| 50–59 | 4 (1.8) | 3 (1.7) | 1 (2.1) | 3 (2.4) | 1 (1) |
| 60–65 | 1 (0.5) | 1 (0.6) | — | — | 1 (1) |
| M (SD) | M (SD) | M (SD) | M (SD) | M (SD) | |
| PSES | 43.13 (16.53) | 43.45 (16.67) | 41.99 (16.14) | 44.54 (16.51) | 41.26 (16.45) |
| Handedness | 0.82 (0.31) | 0.81 (0.32) | 0.85 (0.29) | 0.80 (0.36) | 0.85 (0.29) |
| IQ | 107.05 (11.71) | 107.55 (11.96) | 105.25 (10.71) | 107.48 (11.74) | 106.47 (11.72) |
| n (%) | n (%) | n (%) | n (%) | n (%) | |
| Tobacco use | |||||
| ND yes | 68 (43) | 53 (42.4) | 15 (45.5) | 37 (42) | 31 (44.3) |
| ND no | 90 (57) | 72 (57.6) | 18 (54.5) | 51 (58) | 39 (55.7) |
| No details | 63 | 48 | 15 | 38 | 25 |
| Alcohol use | |||||
| HD yes | 76 (48.1) | 58 (46.4) | 18 (54.5) | 42 (47.7) | 34 (48.6) |
| HD no | 82 (51.9) | 67 (53.6) | 15 (45.5) | 46 (52.3) | 36 (51.4) |
| No details | 63 | 48 | 15 | 38 | 25 |
| Cannabis use | |||||
| Yes | 95 (43) | 77 (44.5) | 18 (37.5) | ||
| No | 126 (57) | 96 (55.5) | 30 (62.5) | ||
| Dailya | 10 (10.5) | 8 (10.4) | 2 (11.1) | ||
| Weekly or lessa | 85 (89.5) | 69 (89.6) | 16 (88.9) | ||
Note: HD, harmful drinking; IQ, Intelligence Quotient; ND, nicotine dependence; PSES, parental socioeconomical status.
aIn those who had ever used cannabis; there were no significant differences between GG subjects and T carrying subjects as well as between cannabis users and cannabis-naïve subjects among demographic measures and substance use (all P > .1).