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. 2014 Nov 24;127(3):924–927. doi: 10.1002/ange.201408113

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© 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

© 2014 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Rupture-force histograms for TERRA G-quadruplexes without ligands (A), with 5 μm cPDS (B), with 50 nm BG4 (C), or with 5 μm cPDS+50 nm BG4 (D). Gaussian fitting (dotted curves) reveal two major populations. The higher force populations are indicated by dotted arrows.