Table 2.

Essential Elements of the Peyronie’s Disease History and Physical Examination

History	Flaccid Penile Exam	Erect Penile Exam (w/ Doppler US)
Onset and progression of symptoms: establish acute versus stable phase	Palpable plaque(s)? Location, size.	Palpable plaque(s)? Location, size.
Penile Deformity: Palpable plaque? Direction and degree of curvature. Impedes intercourse? Presence of hourglass deformity, hinge defect, other anomaly?	Stretched penile length	Plaque(s) visible by US? Location, size, calcification.
Penile Pain? Location, timing (flaccid, erect and/or with penetration), severity/progression	Tenderness to palpation? Location, severity.	Penile Deformity: Degree and direction of curvature. Uniplanar or biplanar? Hourglass deformity? Hinge defect? Other anomaly?
Presence of ED? If yes, pre-existing or new with PD symptoms? Validated questionnaire: IIEF†		Tenderness to palpation? Location, severity.
History of penile trauma? (urologic procedure/surgery, penile fracture, etc.)
History of sexually transmitted infections?
Other medical and surgical history. Diabetes, hypertension, cardiovascular disease.
Social history: Sexual history, smoking/tobacco history, other recreational drug-use
Family history of PD or DD?
Assess distress, overall mood Consider using PDQ

^†IIEF: international Index of Erectile Function