Table 3.
Frequency of NPS and subgroups, ADL functioning and cognition among patients with diagnosed dementia
| Users of anti-dementia drugs | Non-users of anti-dementia drugs | P-value* | |
|---|---|---|---|
| n = 791 | n = 351 | ||
| Frequency of NPS, n (%) | |||
| None | 320 (40.4) | 162 (46.1) | 0.074 |
| One symptom | 252 (31.8) | 114 (32.5) | 0.867 |
| Two to three symptoms | 171 (21.6) | 55 (15.7) | 0.016 |
| Four or more symptoms | 48 (6.1) | 20 (5.7) | 0.771 |
| Any NPS, n (%) | 471 (59.5) | 189 (53.8) | 0.771 |
| Subgroups, n (%) | |||
| Hyperactivity | 264 (33.3) | 116 (33.0) | |
| Psychosis | 105 (13.2) | 36 (10.3) | |
| Mood symptoms and apathy | 299 (37.6) | 90 (25.6) | |
| ADL score, mean (SD) | 58.0 (31.5) | 29.8 (34.5) | <0.001 |
| MMSE, mean (SD) | 16.0 (6.6) | 14.7 (8.0) | 0.011 |
ADL = Barthel Index, scale 0–100
NPS Neuropsychiatric symptoms, MMSE Mini Mental State Examination
*Chi-square test for categorical variables and Student’s t-test for continuous variables