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. Author manuscript; available in PMC: 2016 Aug 1.
Published in final edited form as: J Biomed Mater Res A. 2015 Feb 24;103(8):2747–2757. doi: 10.1002/jbm.a.35399

Figure 2.

Figure 2

The automated thin film stretching method can be applied to a variety of different particle sizes. SEM micrographs of PLGA particles fabricated under (A) sonication, (B) high rpm, (C) medium rpm, and (D) low rpm homogenization. All particles demonstrated a spherical morphology (E, F, G, H). Particle size histograms of the fabricated particles in (A, B, C, D) respectively. SEM micrographs of 2-fold stretched particles under (I) sonication, (J) high rpm, (K) medium rpm, and (L) low rpm homogenization. (M) Aspect ratio analysis of SEM images reveals non-spherical ellipsoidal microparticles can be generated from the thin film stretching procedure.