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. 2014 Mar 13;2:29–31. doi: 10.1016/j.gdata.2014.02.004

Table 2.

Biomarker molecules among the driver genes.

Biomarker gene Biomarker application
ADAM12 Diagnosis
AGR3 Diagnosis
AURKA Efficacy
BCL2 Diagnosis, efficacy, prognosis
CLDN7 Unspecified application
CRP Diagnosis, disease progression, efficacy, prognosis, safety
CYP19A1 Diagnosis, efficacy
DCC Prognosis
EXO1 Diagnosis
FGFR2 Diagnosis, response to therapy
GSTM1 Diagnosis, efficacy, safety
HLTF Diagnosis
ICAM1 Diagnosis, efficacy, prognosis
IDO1 Disease progression, efficacy, prognosis
IGF2BP3 Diagnosis
IL6 Diagnosis, disease progression, efficacy, prognosis, response to therapy, safety
IL6R Efficacy
INHBA Diagnosis
INSR Prognosis
MGMT Diagnosis, efficacy, prognosis
MS4A1 Efficacy, prognosis
MUC4 Diagnosis, disease progression
OVGP1 Diagnosis
PTGS1 Efficacy
PTK2 Diagnosis, disease progression, efficacy, prognosis
PTP4A3 Disease progression
SLC16A1 Diagnosis
SMAD4 Prognosis
STK11 Diagnosis
TP53 Diagnosis, disease progression, efficacy, prognosis, response to therapy
ZNF217 Prognosis