Fig 1. Schematic presentation of experimental design.

C57BL/6 mice in the control group (A) or the pectin treated group (B) were fed with control or pectin diet 168h prior to 14 Gy TBI (n = 3 in each group). One set of mice were euthanized at 24h post-IR for IHC and mRNA analysis. A second set were given BrdUrd at 82h post-IR and then euthanized at 84h for the microcolony assay. The final set of mice was subjected to overall animal survival studies up to 288h post-IR—times of death were noted.