Table 1.
Summary nutrient statistics and univariate analysis results with and without age adjustment
| Risk Factors | Overall (n=152) | Control (n=62) | Case (n=90) | p-value* | OR**(95% CI) | p-value** |
|---|---|---|---|---|---|---|
| Patients characteristics | ||||||
|
| ||||||
| Mean age (sd) | 64.14 (10.93) | 58.23(10.33) | 68.22(9.40) | <0.0001 | 0.11 (1.07,1.15) | <0.0001 |
| Median age (range) | 65 (40–88) | 56 (40–88) | 68.5 (44–87) | |||
|
| ||||||
| Serum Vitamin D level | n(%) | n(%) | n(%) | |||
| Vitamin D deficiency (≤30ng/ml) | 99(65.13) | 42(67.74) | 57(63.33) | 0.51 | 1 | |
| Vitamin D normal (>30 ng/ml) | 51(33.55) | 18(29.03) | 33(36.67) | 1.53(0.70,3.45) | 0.29 | |
|
| ||||||
| Dietary-Nutrition | Mean(SD) | Mean(SD) | Mean(SD) | |||
|
| ||||||
| Quercetin (mg) | 7.19(5.54) | 7.58(5.83) | 6.92(5.34) | 0.48 | 0.99(0.93,1.06) | 0.88 |
|
| ||||||
| Selenium (mcg) | 104.32(64.59) | 104.7(72.75) | 104.06(58.74) | 0.95 | 1.00(1.00,1.01) | 0.18 |
|
| ||||||
| Omega 3(gms) | 1.86(1.21) | 1.89(1.37) | 1.83(1.1) | 0.80 | 1.19(0.88,1.63) | 0.26 |
|
| ||||||
| Lycopene (mcg) | 4000.8(3578.92) | 3925.41 (3168.27.74) | 4052.74 (3852.91) | 0.82 | 1.00(1.00,1.01) | 0.62 |
|
| ||||||
| Total fat (gms) | 80.23(52.98) | 83.05(5.82) | 78.3(42.23) | 0.62 | 1.00(1.00,1.01) | 0.40 |
|
| ||||||
| Saturated fat (gms) | 24.05(17.81) | 25.27(22.23) | 23.20(14.06) | 0.52 | 1.01(0.99,1.03) | 0.50 |
|
| ||||||
| Polyunsaturated fat (gms) | 18.49(11.2) | 18.86(13.31) | 18.20(9.55) | 0.75 | 1.02(0.99,1.05) | 0.30 |
|
| ||||||
| Monounsaturated fatty acids (gms) | 31.13(20.61) | 32.19(25.88) | 30.40(16.13) | 0.63 | 1.01(0.99,1.03) | 0.42 |
|
| ||||||
| % of Kcal from fat | 35.95(7.11) | 35.90(7.73) | 35.98(6.69) | 0.95 | 1.00(0.95,1.05) | 0.93 |
|
| ||||||
| Trans fats, total (gms) | 2.66(2.24) | 2.78(2.82) | 2.57(1.74) | 0.59 | 1.07(0.91,1.26) | 0.44 |
|
| ||||||
| Food folate (mcg) | 290.77 (162.15) | 295.06(157.05) | 287.81(166.38) | 0.79 | 1.00(1.00,1.00) | 0.42 |
|
| ||||||
| Folic acid (mcg) | 153.13(133.1) | 150.18(139.27) | 155.17(129.44) | 0.82 | 1.00(1.00,1.00) | 0.38 |
|
| ||||||
| Growth hormone stimulation test (mg) | 40.82(26.44) | 43.36(31.66) | 39.07.06(22.17) | 0.36 | 1.00(0.99,1.02) | 0.69 |
|
| ||||||
| Growth hormone secretagogue receptor (mg) | 27.11(17.58) | 28.71(20.79) | 26.01(15.00) | 0.38 | 1.00(0.98,1.03) | 0.68 |
|
| ||||||
| Thiamine (mg) | 1.63(0.92) | 1.61(0.99) | 1.64(0.88) | 0.88 | 1.27(0.86,1.92) | 0.23 |
|
| ||||||
| Isoflavones (mg) | 2.73(6.9) | 2.48(6.62) | 2.91(7.11) | 0.71 | 1.02(0.97,1.10) | 0.40 |
|
| ||||||
| Vitamin D (IU) | 146.65(115.43) | 153.26(119.53) | 142.09(112.96) | 0.56 | 1.00(1.00,1.00) | 0.61 |
|
| ||||||
| Fruit servings (servings/day) | 1.39(0.9) | 1.44(0.92) | 1.36(0.90) | 0.57 | 0.92(0.61,1.37) | 0.68 |
|
| ||||||
| Fruit (total including juice) (cup) | 1.21(0.84) | 1.22(0.74) | 1.21(0.91) | 0.90 | 1.18(0.77,1.84) | 0.44 |
|
| ||||||
| Dietary – Supplement | n(%) | n(%) | n(%) | |||
|
| ||||||
| Selenium, folic acid or Vitamin D or E - No | 76(50) | 28(45.16) | 48(53.33) | 0.41 | 1 | |
| Selenium, folic acid or Vitamin D or E - Yes | 76(50) | 34(54.84) | 42(46.67) | 0.56(0.26,1.16) | 0.12 | |
|
| ||||||
| Omega 3 or 6 - No | 135(88.82) | 48(77.42) | 87(96.67) | 3e-04 | 1 | |
| Omega 3 or 6 - Yes | 17(11.18) | 14(22.48) | 3(3.33) | 0.10(0.02,0.35) | 0.0012 | |
*
p-values indicated the testing results for differences between case and control by t-test in continuous outcomes, or a Fisher exact test in categorical outcomes.
**
OR(95%CI): odds ratio and 95% confidence interval, and p-values were results from logistic regression models with age adjusted (not shown).
SD, standard deviation. Plus-minus values are means ± SD.