TABLE 5.
Performance characteristics of regression models
| Regression models | AUC | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Correctly classified (%) |
|---|---|---|---|---|---|---|
| TACO vs. TRALI (n =99)* | ||||||
| Clinical model | 0.88 | 90 | 66 | 86 | 73 | 83 |
| Cytokine model | 0.88 | 93 | 59 | 84 | 77 | 83 |
| Combined model | 0.96 | 93 | 90 | 96 | 84 | 92 |
| Limited clinical/cytokine | ||||||
| TACO vs. TRALI (n =99)* | 0.97 | 96 | 83 | 93 | 88 | 92 |
| TACO vs. possible | 0.93 | 91 | 89 | 93 | 86 | 91 |
| TRALI (n =77)* | ||||||
| TRALI vs. possible | 0.87 | 83 | 72 | 81 | 74 | 78 |
| TRALI (n =118)* | ||||||
*
Numbers in parentheses represent the combined numbers of subjects compared in the model.
NPV =negative predictive value; PPV =positive predictive value.