Selective laser-triggered rupture and release of enzymes. (A, B) Bright-field and fluorescent optical images of 650 and 785 nm ruptured capsules showing release of HRP (monitored by Amplex Red), respectively, with release rate controlled by the ruptured area of the PLGA polymer shell (edge length of the square images: 300 µm) (C, D) Plots showing release of HRP from ruptured capsule arrays, demonstrating orthogonal selectivity of AuNR-encrusted capsules as well as fine control over release kinetics, monitored by an ABTS substrate (N = 3).