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. Author manuscript; available in PMC: 2016 Aug 11.
Published in final edited form as: Cell Rep. 2015 Jul 30;12(6):1056–1068. doi: 10.1016/j.celrep.2015.07.019

Figure 1. Phylogeny and ASR of AAV evolutionary lineage.

Figure 1

Maximum-likelihood phylogeny relating 75 isolates of AAV). Red circles represent evolutionary intermediates reconstructed through ASR. Blue circle represents library of probabilistic sequence space around Anc80. Subclades are collapsed for clarity. Full phylogeny and sequence alignment is presented in Supplementary Figure S3 and S2.