Skip to main content
. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Antiviral Res. 2015 Jul 2;121:109–119. doi: 10.1016/j.antiviral.2015.07.001

Fig. 2.

Fig. 2

L. plantarum introduced after virus challenge limits virus recovery and virus-induced inflammation. (A) Virus titer in lung tissue on day 5 after inoculation with PVM from mice that received intranasal inoculations of hi Lp, 108 cells/mouse on d1 or on d1 and d2; *p < 0.05; **p < 0.01 vs. pbs/bsa. (B) Formalin-fixed, hematoxylin and eosin-stained lung tissue from mice inoculated on d1 and d2 as described in the legend to (A); arrows in panel i. point to areas of inflammation. (C) Proinflammatory cytokines IL-6, CCL2, and CXCL10 in lung tissue of mice inoculated as in the legend to (A); *p < 0.05; **p < 0.01. (D) Proinflammatory cytokines IL-6 and CCL2 in lung tissue on day 5 after inoculation with PVM from mice that received intranasal inoculations of live Lp, 108 cells/mouse on d1 and d2; **p < 0.01.