Table 3.

Significant associations between the number of CD symptoms and axial and radial diffusivity in white matter tracts, including tests of interactions with gender and race-ethicity.

Measure	Contrast	Region	MNI coordinates			Cluster size	Peak t	TFCE-corrected p	Cohen’s d
			x	y	z
Axial Diffusivity
	CD Symptoms
		Left corticospinal tract	−5	−26	−35	9137	5.71	0.029	1.09
		Right superior longitudinal fasciculus	19	−2	46	3002	3.97	0.038	0.76
		Right cerebellum (vermis)	10	−58	−20	305	3.73	0.049	0.71
		Right cerebellum (vermis)	8	−66	−24	105	3.78	0.049	0.72
		Right forceps minor	18	44	26	69	4.16	0.049	0.80
		Right forceps major	22	−63	35	68	5.77	0.050	1.11
	CD Symptoms x Gender
		Left corticospinal tract	−8	−25	−29	21150	5.98	0.018	1.15
		Right inferior longitudinal fasciculus	44	−30	7	1249	3.16	0.044	0.61
		Cerebellum (vermis)	5	−51	−17	965	5.37	0.043	1.03
		Right anterior thalamic radiation	19	−33	4	78	5.18	0.048	0.99
	CD Symptoms x Race-Ethnicity
		Left corticospinal tract	−16	−16	−11	18455	3.21	0.007	0.61
		Right superior longitudinal fasciculus	21	−8	45	11218	3.39	0.010	0.65
		Right inferior fronto-occipital fasciculus	25	−77	23	156	3.39	0.049	0.65
		Right forceps major	13	−83	27	40	3.55	0.050	0.68
		Right forceps major	10	−85	24	3	3.67	0.050	0.70
		Left inferior longitudinal fasciculus	−48	−18	−4	3	3.55	0.050	0.68
Radial Diffusivity
	CD Symptoms x Gender
		Right superior longitudinal fasciculus	35	−18	26	54781	4.65	0.008	0.89
		Left uncinate fasciculus	−19	5	−13	39	3.40	0.050	0.65
		Left corticospinal tract	−22	−45	50	35	3.77	0.050	0.72
		Right anterior thalamic radiation	1	−5	−11	7	4.39	0.050	0.84
	CD Symptoms x Race-Ethnicity
		Right corticospinal tract	6	−25	−12	62055	3.47	0.007	0.66

All reported effects significant at FWE p < .05.