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. 2015 Aug 13;10(8):e0135294. doi: 10.1371/journal.pone.0135294

Table 3. Anthropometric, Metabolic and Cardiovascular Risk Parameters of Study Subjects by Tertiles of Maximum Target-to-Background Ratio (maxTBR) value.

MaxTBR T1 (0.83–1.15) MaxTBR T2 (1.16–1.35) MaxTBR T3 (1.36–2.35) P P’
Sex, male (%) 16 (50.0) 16 (53.3) 21 (67.7) 0.322
Age (years) 50.8 ± 8.6 49.0 ± 10.0 52.1 ± 10.2 0.461
BMI (kg/m2) 22.3 (19.2, 24.2)a 25.0 (23.7, 26.8)b 25.4 (23.7, 26.9)b <0.001 <0.001
Waist circumference (cm) 79.1 ± 8.0a 85.2 ± 7.0b 87.5 ± 6.5b <0.001 <0.001
SBP (mmHg) 120.0 (111.0, 125.0)a 126.0 (118.0, 133.0)ab 127.0 (118.0, 143.0)b 0.018 0.005
DBP (mmHg) 78.4 ± 8.8a 82.6 ± 10.5ab 87.8 ± 11.9b 0.003 0.009
Triglycerides (mmol/L) 0.8 (0.6, 1.0)a 1.6 (1.0, 2.3)b 1.4 (1.2, 2.2)b <0.001 <0.001
HDL-C (mmol/L) 1.3 ± 0.4 1.2 ± 0.3 1.2 ± 0.3 0.516 0.489
LDL-C (mmol/L) 2.6 (2.0, 3.8)a 2.9 (2.4, 4.3)ab 3.8 (3.4, 4.3)b <0.001 <0.001
Glucose (mmol/L) 4.5 ± 0.9a 5.0 ± 0.8b 5.5 ± 0.7b <0.001 <0.001
hsCRP (mg/L) 0.4 (0.2, 0.8)a 1.5 (0.5, 3.1)b 3.2 (2.6, 4.8)c <0.001 <0.001
HOMA-IR 0.3 (0.2, 0.7)a 0.8 (0.5, 1.2)b 1.0 (0.5, 1.6)b <0.001 <0.001
Current smoker (%) 10 (31.2) 8 (26.7) 9 (29.0) 0.924 0.688
VFA (cm2) 84.8 ± 35.9a 101.7 ± 30.0a 129.2 ± 34.2b <0.001 <0.001
SFA (cm2) 146.4 ± 48.4a 197.0 ± 67.2b 193.0 ± 49.0b 0.001 <0.001
PAT (cm3) 157.4 (116.3, 205.1)a 233.6 (171.2, 285.1)b 272.6 (185.5, 317.5)b <0.001 <0.001

BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; hsCRP, high sensitivity C-reactive protein; HOMA-IR, homeostasis model assessment insulin resistance; VFA, (abdominal) visceral fat area; SFA, (abdominal) subcutaneous fat area; PAT, pericardial adipose tissue.

Data are mean ± SD, median (interquartile range), or N (%).

Means or medians with the different letter are significantly different.

The variables expressed as medians (interquartile range) were assessed by the the Mann-Withney test in multiple comparisons, and the P-values were adjusted by the Bonferoni correction (P <0.017 was considered statistically significant).

P’ values were calculated after adjusting for age and sex by using the analysis of covariance (ANCOVA) for continuous variables and a logistic regression analysis for categorical variables.