Table 3. Anthropometric, Metabolic and Cardiovascular Risk Parameters of Study Subjects by Tertiles of Maximum Target-to-Background Ratio (maxTBR) value.
MaxTBR T1 (0.83–1.15) | MaxTBR T2 (1.16–1.35) | MaxTBR T3 (1.36–2.35) | P | P’ | |
---|---|---|---|---|---|
Sex, male (%) | 16 (50.0) | 16 (53.3) | 21 (67.7) | 0.322 | |
Age (years) | 50.8 ± 8.6 | 49.0 ± 10.0 | 52.1 ± 10.2 | 0.461 | |
BMI (kg/m2) | 22.3 (19.2, 24.2)a | 25.0 (23.7, 26.8)b | 25.4 (23.7, 26.9)b | <0.001 | <0.001 |
Waist circumference (cm) | 79.1 ± 8.0a | 85.2 ± 7.0b | 87.5 ± 6.5b | <0.001 | <0.001 |
SBP (mmHg) | 120.0 (111.0, 125.0)a | 126.0 (118.0, 133.0)ab | 127.0 (118.0, 143.0)b | 0.018 | 0.005 |
DBP (mmHg) | 78.4 ± 8.8a | 82.6 ± 10.5ab | 87.8 ± 11.9b | 0.003 | 0.009 |
Triglycerides (mmol/L) | 0.8 (0.6, 1.0)a | 1.6 (1.0, 2.3)b | 1.4 (1.2, 2.2)b | <0.001 | <0.001 |
HDL-C (mmol/L) | 1.3 ± 0.4 | 1.2 ± 0.3 | 1.2 ± 0.3 | 0.516 | 0.489 |
LDL-C (mmol/L) | 2.6 (2.0, 3.8)a | 2.9 (2.4, 4.3)ab | 3.8 (3.4, 4.3)b | <0.001 | <0.001 |
Glucose (mmol/L) | 4.5 ± 0.9a | 5.0 ± 0.8b | 5.5 ± 0.7b | <0.001 | <0.001 |
hsCRP (mg/L) | 0.4 (0.2, 0.8)a | 1.5 (0.5, 3.1)b | 3.2 (2.6, 4.8)c | <0.001 | <0.001 |
HOMA-IR | 0.3 (0.2, 0.7)a | 0.8 (0.5, 1.2)b | 1.0 (0.5, 1.6)b | <0.001 | <0.001 |
Current smoker (%) | 10 (31.2) | 8 (26.7) | 9 (29.0) | 0.924 | 0.688 |
VFA (cm2) | 84.8 ± 35.9a | 101.7 ± 30.0a | 129.2 ± 34.2b | <0.001 | <0.001 |
SFA (cm2) | 146.4 ± 48.4a | 197.0 ± 67.2b | 193.0 ± 49.0b | 0.001 | <0.001 |
PAT (cm3) | 157.4 (116.3, 205.1)a | 233.6 (171.2, 285.1)b | 272.6 (185.5, 317.5)b | <0.001 | <0.001 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; hsCRP, high sensitivity C-reactive protein; HOMA-IR, homeostasis model assessment insulin resistance; VFA, (abdominal) visceral fat area; SFA, (abdominal) subcutaneous fat area; PAT, pericardial adipose tissue.
Data are mean ± SD, median (interquartile range), or N (%).
Means or medians with the different letter are significantly different.
The variables expressed as medians (interquartile range) were assessed by the the Mann-Withney test in multiple comparisons, and the P-values were adjusted by the Bonferoni correction (P <0.017 was considered statistically significant).
P’ values were calculated after adjusting for age and sex by using the analysis of covariance (ANCOVA) for continuous variables and a logistic regression analysis for categorical variables.