Table 3. Tajima’s D and iHS values for CHRNB3-CHRNA6 region.
| SNP | Function | EUR Freq | Tajima's D EUR | iHS EUR | ASN Freq | Tajima's D ASN | iHS ASN | AFR Freq | Tajima's D AFR | iHSAFR |
|---|---|---|---|---|---|---|---|---|---|---|
| rs1979140 | intergenic | 0.77 | (-0.75, -0.34) | -1.44 | 0.82 | (-1.21, -1.15) | -0.47 | 0.28 | (-1.26, -0.99) | -0.15 |
| rs7816726 | intergenic | 0.77 | (0.33, 1.00) | -1.44 | 0.81 | (-0.02, 0.70) | -0.49 | 0.28 | (0.08, 0.17) | -0.56 |
| rs10958726 | intergenic | 0.23 | (0.1, 0.68) | 2.46 | 0.18 | (-0.85, -0.15) | 1.06 | 0.63 | (-0.70, 0.18) | 0.65 |
| rs7842601 | intergenic | 0.23 | (0.17, 0.62) | 2.58 | 0.18 | (-0.33, -0.17) | 1.06 | 0.63 | (0.63, 1.33) | 0.84 |
| rs13273442 | intergenic | 0.23 | (-0.39, 0.69) | 2.32 | 0.18 | (-0.60, -0.45) | 1.02 | 0.63 | (-0.75, 0.04) | -0.21 |
| rs9792277 | intergenic | 0.77 | (1.56, 1.80) | -1.45 | 0.81 | (1.06, 1.17) | -0.54 | 0.33 | (1.38, 2.32) | 0.77 |
| rs1451239 | intergenic | 0.77 | (2.41, 2.58) | -1.45 | 0.82 | (1.34, 1.40) | -0.46 | 0.34 | (2.18, 2.51) | 0.89 |
| rs1451240 | intergenic | 0.23 | (2.41, 2.54) | 2.48 | 0.18 | (1.33, 1.41) | 1.11 | 0.67 | (2.18, 2.46) | 0.09 |
| rs1901281 | intergenic | 0.77 | (2.37, 2.68) | -1.56 | 0.81 | (1.26, 1.33) | -0.54 | 0.28 | (2.18, 2.19) | 0.37 |
| rs4736835 | intergenic | 0.23 | (2.48, 2.68) | 2.6 | 0.18 | (1.17, 1.26) | 1.11 | 0.66 | (1.47, 2.63) | -0.08 |
| rs1955185 | intergenic | 0.77 | (1.49, 1.67) | -1.58 | 0.82 | (0.64, 0.69) | -0.52 | 0.28 | (1.08, 1.59) | 0.54 |
| rs13277254 | intergenic | 0.23 | (0.89, 1.27) | 2.69 | 0.18 | (0.64, 0.97) | 1.32 | 0.63 | (1.11, 1.29) | -0.6 |
| rs13277524 | intergenic | 0.77 | (0.64, 0.89) | -1.63 | 0.82 | (0.24, 0.97) | -0.65 | 0.28 | (0.43, 1.29) | 0.61 |
| rs6474412 | intergenic | 0.77 | (1.09, 1.43) | -1.63 | 0.82 | (0.53, 0.66) | -0.65 | 0.34 | (1.01, 1.49) | 1.25 |
| rs6474413 | intergenic | 0.77 | (1.86, 2.19) | -1.66 | 0.82 | (0.13, 0.22) | -0.65 | 0.28 | (1.15, 1.33) | 0.62 |
| rs7004381 | intergenic | 0.23 | (0.68, 1.86) | 2.72 | 0.18 | (-0.15, 0.22) | 1.32 | 0.63 | (0.29, 1.15) | -0.72 |
| rs6985052 | intergenic | 0.77 | (-0.37, 0.68) | -1.66 | 0.82 | (-0.85, -0.16) | -0.65 | 0.29 | (-1.04, -0.29) | 0.71 |
| rs4950 | CHRNB3 5'UTR | 0.23 | (-0.39, 0.12) | 2.71 | 0.18 | (-0.44, -0.16) | 1.31 | 0.8 | (0.38, 1.55) | 0.25 |
| rs9643891 | CHRNB3 intronic | 0.77 | (-0.34, 0.13) | -1.85 | 0.82 | (0.60, 0.72) | -1.01 | 0.15 | (-0.65, -0.16) | -0.15 |
| rs9643853 | CHRNB3 intronic | 0.77 | (-1.04, -0.34) | -1.89 | 0.82 | (-0.60, 0.60) | -1.01 | 0.15 | (-1.55, -0.65) | -0.1 |
| rs13280604 | CHRNB3 intronic | 0.23 | (0.47, 1.68) | 2.9 | 0.18 | (0.07, 0.50) | 1.94 | 0.8 | (0.04, 0.83) | 0.12 |
| rs6997909 | CHRNB3 intronic | 0.77 | (0.70, 0.70) | -1.88 | 0.82 | (-0.25, 0.11) | -1.19 | 0.15 | (-1.00, -1.00) | 0 |
| rs6474414 | CHRNB3 intronic | 0.77 | (0.40, 0.40) | -1.88 | 0.82 | (-0.60, -0.21) | -1.19 | 0.15 | (-0.76, -0.12) | 0 |
| rs6474415 | CHRNB3 intronic | 0.23 | (1.26, 1.35) | 3.07 | 0.18 | (-0.12, 0.22) | 1.97 | 0.85 | (-0.85, -0.52) | 0.84 |
| rs4236926 | CHRNB3 intronic | 0.77 | (-0.04, -0.03) | -1.71 | 0.81 | (-0.14, -0.11) | -1.41 | 0.15 | (-0.54, -0.54) | 0.14 |
| rs16891561 | CHRNB3 intronic | 0.77 | (-1.28, -0.90) | -1.67 | 0.81 | (-0.89, 0.72) | -1.26 | 0.15 | (-1.08, -0.48) | 0.2 |
| rs55828312 | CHRNB3 intronic | 0.24 | (-(0.89, -0.74) | 2.86 | 0.19 | (-1.13, -0.31) | 2.13 | 0.83 | (-0.85, 0.67) | 1.12 |
All SNPs have r2 value of 0.8 or greater with rs1451240. Significant values and SNP names are bolded.