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. Author manuscript; available in PMC: 2016 Jul 1.

Published in final edited form as: Clin Pharmacol Ther. 2015 May 2;98(1):25–33. doi: 10.1002/cpt.127

Table 4.

Change in clinic blood pressure by dose group in lisinopril-naïve patients

	Baseline BP (mmHg)	Lisinopril BP (mmHg)	Change in BP from baseline
	Baseline BP (mmHg)	Lisinopril BP (mmHg)	Mean	95% CI
Trough (pre-dose)
Systolic
0.1 mg/kg (n=6)	121.2 ± 3.9	115.3 ± 7.6	−5.8	(−13.9, 2.2)
0.2 mg/kg (n=5)	129.6 ± 6.7	117.6 ± 6.5	−12	(−19.6, −4.4)
0.4 mg/kg (n=2)	124.5 ± 9.2	113.5 ± 6.4	−11	N/A
Diastolic
0.1 mg/kg (n=6)	75.7 ± 12.8	69.2 ± 6.6	−6.5	(−21, 8)
0.2 mg/kg (n=5)	73.8 ± 7.5	68.2 ± 11.8	−5.6	(−15, 3.8)
0.4 mg/kg (n=2)	76.5 ± 16.3	69.5 ± 14.8	−7	N/A

Data are mean ± SD. BP, blood pressure; CI, confidence interval.