Fig. 2.

Native renal biopsies (a–d). Transmission electron micrograph images from IV.3 (a, b) and IV.5 (c, d), with higher magnification images in the bottom row (b, d). In IV.3, the GBM was thin, with a diameter as low as 92 nm. There were also focal areas of lamination (black arrow in a). In IV.5, glomerular basement membranes extra cellular matrix (GBMs) were irregular, with thick and thin portions, with lamination (black arrow in c). There was extensive podocyte foot process fusion and a generalized increase in the mesangium