Table 2.
The column labeled “PET prediction asymmetries” shows values used as input to the prediction, and correspond to asymmetries of PET-mesial, PET-hippo-var, and PET-entire-var, respectively. Surgeries for “New TLE” were performed during the past 12 months. Abbreviations: L = left, R = right, TL = temporal lobe, MTS = mesial temporal sclerosis, ATL = anterior temporal lobectomy, CPS = complex partial seizures, GTCS = generalized tonic-clonic seizures, SPS = simple partial seizures, w/2° GTCS = with secondary generalization, rare GTCS = ten or less GTCS episodes in lifetime.
| ID | Seizure type |
Ictal EEG |
MRI inspection | PET inspection |
Clinical decision | PET prediction asymmetries | Probabilistic classification | 95% CI posterior probability | Surgery + outcome |
|---|---|---|---|---|---|---|---|---|---|
| New TLE | |||||||||
| 1-LO | CPS, CPS w/2° GTCS |
L TL electrodes | L MTS | L anter. TL hypo. | LTLE | 0.01553 −0.00439 −0.02010 |
LTLE 99.72% |
[0.027–0.339] |
ATL + Class I |
| 2-FU |
CPS, rareGTCS | L TL and frontal electrodes | Unremarkable | Bil. TL hypo, biased to left | LTLE | 0.04544 0.15939 −0.02126 |
LTLE 100% |
[0–0.01] |
n.a. |
| 3-RA | CPS | L frontal electrodes | Unremarkable | L later. TL hypo. | LTLE | 0.00434 −0.08219 0.07710 |
LTLE 99.64% |
[0.04–0.36] |
Implants + ATL + Class I |
| 4-NE | CPS, GTCS |
L frontal electrodes | L MTS | L TL hypo. | LTLE | 0.03004 0.33749 0.08012 |
LTLE 100% |
[0–0.05] |
Laser ablation + Class I |
| 5-GM | CPS, rare GTCS | R Temporal electrodes | R MTS | R TL hypo. | RTLE | −0.05851 −0.20535 −0.16405 |
RTLE 100% |
[0.99–1] |
Laser ablation + Class I |
| 6-OL | SPS, CPS, CPS w/2° GTCS |
R TL electrodes | R MTS | R TL hypo. | RTLE | −0.03744 0.05089 0.12806 |
RTLE 98.47% |
[0.63–0.99] |
ATL + Class I |
| 7-NL | SPS, CPS |
R TL electrodes | General atrophy, larger R amygdala | Mild R mesial TL hypo. | RTLE | −0.02331 0.20569 0.05303 |
RTLE 96.33% |
[0.44–0.99] | ATL + Class I |
| Ambiguous cases | |||||||||
| 1-RD | CPS, rare GTCS | L TL electrodes | Hyperintensity in R frontal, R periventricular, L caudate, and mild R hippocampal atrophy | Bilateral hypo, biased to left | LTLE | 0.00729 −0.04469 0.03298 |
LTLE 99.49% |
[0.075–0.389] | Implants + ATL + Class I |
| 2-VO | SPS, CPS |
L TL electrodes | L MTS | Bilateral hypo. | LTLE | 0.02933 0.05192 −0.04924 |
LTLE 99.97% |
[0.001–0.157] | Laser ablation + Class I |
| 3-VD | CPS | L TL electrodes | L MTS | Bilateral hypo. | LTLE | 0.04426 0.17092 0.08998 |
LTLE 100% |
[0–0.004] | ATL + Class I |
| 4-CS | CPS, CPS w/2° GTCS |
L TL electrodes | Unremarkable | Unremarkable | LTLE | 0.02901 0.12306 0.15600 | LTLE 100% |
[0–0.01] | Implants + ATL + Class I |
| 5-LN | SPS, CPS |
L TL electrodes | Unremarkable | Unremarkable | LTLE | −0.01649 −0.35912 0.06109 |
RTLE 90.53% |
[0.289–0.981] | Implants + ATL + Class I |