Skip to main content
. 2015 Jul 7;290(33):20284–20294. doi: 10.1074/jbc.M115.658625

FIGURE 4.

FIGURE 4.

miR-184 regulates the β-cell secretome. A, identification of secreted factors that were inhibited after a high glucose stimulus of 184-mimic-transfected “light” compared with Ctrl-mimic transfected “heavy” MIN6 cells after SILAC labeling. B, Venn diagram representation of the secreted factors of MIN6 cells transfected with 184-mimic (from the current study) and from MIN6 cells treated with high/low glucose and si-Gck (taken from Tattikota et al. (26)) having a cutoff value of 0.5 log 2-fold change. C and D, intersection of the secretome profiles of MIN6 cells transfected with 184-mimic (from the current study) and of MIN6 cells treated with high/low glucose and si-Gck (taken from Tattikota et al. (26)) displays an inverse and positive correlation, respectively.