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. 2015 Aug 14;11:206. doi: 10.1186/s12917-015-0505-7

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© Brown et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Effects of LLL12 on transcriptional targets of STAT3. Feline OSCC cells were treated with DMSO or 0.2 μM LLL12 for 12 h and RNA and protein were collected. Quantitative RT-PCR (a) and Western blotting (b) were performed to assess survivin mRNA and protein levels, respectively (*p < 0.0001). (c) Quantitative RT-PCR was performed to assess cyclin D1, MCL-1, VEGF and HIF1α mRNA expression in the cells treated above (*p < 0.05)