Table 2.
Multivariable logistic regression
| Variable | ≥1 Positive LN (N = 343) | ≥4 Positive LN (N = 149) | ||
|---|---|---|---|---|
| OR (95 % CI) | p value | OR (95 % CI) | p value | |
| Subtypeª | 0.227 | 0.561 | ||
| Luminal A | 1 | 1 | ||
| luminalHer2− | 0.7 (0.4–1.2) | 1.0 (0.5–2.0) | ||
| luminalHer2+ | 0.7 (0.4–1.4) | 1.1 (0.5–2.7) | ||
| TNBC | 0.7 (0.4–1.2) | 0.8 (0.4–1.7) | ||
| Her-2+ | 1.2 (0.6–2.1) | 1.4 (0.7–3.0) | ||
| Tumor size (cm) | <0.0001 | 0.001 | ||
| <2 | 1 | 1 | ||
| 2~5 | 2.3 (1.6–3.4) | 2.4 (1.5–4.0) | ||
| >5 | 2.7 (0.7–10.2) | 6.2 (1.5–26.4) | ||
| Grade | <0.0001 | 0.015 | ||
| 1 | 1 | 1 | ||
| 2 | 5.6 (2.8–11.2) | 17.5 (2.4–130.5) | ||
| 3 | 4.5 (2.1–9.8) | 22.9 (3.0–176.3) | ||
| Age level | 0.548 | 0.676 | ||
| <50 | 1 | 1 | ||
| 50–79 | 0.9 (0.6–1.3) | 1.1 (0.7–1.8) | ||
| >79 | 2.1 (0.3–13.1) | 2.1 (0.3–13.8) | ||
Bold values are statistically significant (p < 0.05)
LN lymph node, OR odds ratio
ªSubtypes as defined as luminal A (ER+/PR+, HER2−, Ki67 < 14 % or PR ≥ 20 %), luminalHer2− (ER+/PR+, HER2−, Ki67 ≥ 14 % or PR < 20 %), luminalHer2+ (ER+ and HER-2+), TNBC (ER− and PR− and HER2−) and HER-2+ (ER− and PR− and HER-2+)