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Relative risk of overall malignancy in patients with rheumatoid arthritis (RA) compared with the general population. CI, confidence interval; DMARD, disease-modifying antirheumatic drug; n, number of malignancies; N, population size; RR, relative risk; SIR, standardized incidence ratio; TNF, tumor necrosis factor. *SIRs by sex are not included in the total pooled SIR. †Excluding non-melanoma skin cancer. ‡All solid tumors. §Excluding lymphatic and hematopoietic
