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. Author manuscript; available in PMC: 2015 Aug 14.
Published in final edited form as: Curr Opin Rheumatol. 2012 Jul;24(4):401–407. doi: 10.1097/BOR.0b013e328353372d

Figure 1. Role of IL-23/p40 in CVB3 myocarditis.

Figure 1

Male WT BALB/c and IL-12p40 deficient (p40−/−) mice were inoculated ip with 103 PFU of heart-passaged CVB3+heart proteins on day 0 and A) myocarditis, B) viral replication, and C) cytokines assessed at day 10 pi. IL-23/p40 deficiency did not alter myocarditis, viral replication or cytokine levels in the heart, except for reducing IL-12/IL-23p40 levels. Data show the mean ±SEM from one of three experiments using 7–10 mice/group. P values were evaluated using the Student’s t and/or Mann-Whitney rank tests.