Table 3.
Accuracy of frozen section for predicting predominant histologic subtype and presence or absence of histologic patterns in permanent sections
| Parameter | Accuracy, % (95% CI) | Sensitivity, % (95% CI) | Specificity, % (95% CI) | κ |
|---|---|---|---|---|
| Predominant histologic subtype | ||||
| Overall | 68 (63–73) | NA | NA | 0.565 |
| Lepidic | 90 (86–92) | 75 (64–84) | 93 (90–96) | 0.681 |
| Acinar | 76 (71–80) | 70 (61–77) | 79 (73–84) | 0.481 |
| Papillary | 85 (81–88) | 62 (50–72) | 91 (87–94) | 0.527 |
| Micropapillary | 94 (91–96) | 21 (9–40) | 99 (97–100) | 0.277 |
| Solid | 91 (88–94) | 79 (67–87) | 94 (90–96) | 0.700 |
| Presence or absence of histologic pattern | ||||
| Lepidic | 80 (76–84) | 75 (69–80) | 91 (84–96) | 0.588 |
| Acinar | 89 (85–92) | 90 (86–93) | 67 (35–90) | 0.252 |
| Papillary | 72 (67–77) | 70 (64–75) | 79 (69–87) | 0.397 |
| Micropapillary | 67 (62–72) | 37 (30–45) | 94 (89–97) | 0.321 |
| Solid | 84 (80–88) | 69 (61–76) | 96 (92–98) | 0.670 |
NA, not applicable