TABLE 1.
Baseline Demographic and Clinical Characteristics of Patients With PH-LHD and HFpEF
| Total Population (n = 73) |
Iso-PH (n = 47) |
Comb-PH (n = 26) |
|
|---|---|---|---|
| Age, yrs | 69 ± 12 | 70 ± 12 | 67 ± 11 |
| Female | 54 (74) | 33 (70) | 21 (81) |
| Body mass index, kg/m2 | 33 ± 10 | 32 ± 10 | 34 ± 10 |
| Non-Hispanic White | 68 (93) | 44 (94) | 24 (92) |
| NYHA functional class (n = 69) | |||
| I | 2 (3) | 2 (4) | 0 (0) |
| II | 33 (48) | 22 (49) | 11 (46) |
| III | 28 (40) | 17 (38) | 11 (46) |
| IV | 6 (9) | 4 (9) | 2 (8) |
| Comorbidities | |||
| Atrial fibrillation | 32 (44) | 21 (45) | 11 (42) |
| Coronary artery disease | 23 (32) | 14 (30) | 9 (35) |
| Diabetes mellitus | 22 (30) | 14 (30) | 8 (31) |
| Hyperlipidemia | 37 (51) | 23 (49) | 14 (54) |
| Hypertension | 55 (75) | 38 (81) | 17 (65) |
| Obstructive sleep apnea | 28 (38) | 18 (38) | 10 (38) |
| Follow-up, yrs* | 3.6 (4.5) | 3.7 (2.3) | 3.5 (2.1) |
| Death | 25 (34) | 16 (34) | 9 (35) |
Values are mean ± SD or n (%).
*
Values in parentheses are the difference between the 25th and 75th percentiles.
Comb-PH = combined post-capillary pulmonary hypertension and pre-capillary pulmonary hypertension; HFpEF = heart failure with preserved ejection fraction; Iso-PH = isolated post-capillary pulmonary hypertension; NYHA = New York Heart Association; PH-LHD = pulmonary hypertension due to left heart disease.