TABLE 5.
Baseline Demographic and Hemodynamic Characteristics of Patients by Acute Vasodilator Testing Status (n = 73)
| Acute Vasodilator Responders* (n = 10) |
Nonresponders (n = 47) |
Not Tested (n = 16) |
|
|---|---|---|---|
| Baseline clinical data | |||
| Age, yrs | 66 ± 15 | 69 ± 11 | 73 ± 10 |
| Female | 10 (100) | 33 (70) | 11 (69) |
| Body mass index, kg/m2 | 40 ± 17 | 32 ± 9 | 29 ± 6 |
| Non-Hispanic White | 10 (100) | 42 (89) | 16 (100) |
| NYHA functional class (n = 69) | |||
| I | 0 (0) | 1 (2) | 1 (7) |
| II | 4 (40) | 23 (52) | 6 (40) |
| III | 4 (40) | 17 (39) | 7 (46) |
| IV | 2 (20) | 3 (7) | 1 (7) |
| Hemodynamic data | |||
| Heart rate, beats/min | 79 ± 13 | 73 ± 15 | 64 ± 6 |
| Mean arterial pressure, mm Hg | 96 ± 10 | 97 ± 15 | 97 ± 14 |
| Mean RA pressure, mm Hg | 13 ± 5 | 13 ± 4 | 14 ± 7 |
| Mean PA pressure, mm Hg | 41 ± 12 | 41 ± 11 | 41 ± 12 |
| PAWP, mm Hg | 20 ± 3 | 21 ± 4 | 23 ± 6 |
| Pulse pressure, mm Hg | 36 ± 19 | 36 ± 14 | 43 ± 17 |
| TPG, mm Hg | 21 ± 12 | 20 ± 10 | 18 ± 8 |
| Thermodilution CO, l/min1 | 4.8 ± 1.6 | 4.9 ± 1.5 | 4.2 ± 1.3 |
| PAC, ml/mm Hg | 2.3 ± 1.8 | 2.2 ± 1.1 | 1.7 ± 0.7 |
| SAC (n = 70), ml/mm Hg | 1.1 ± 0.5 | 1.2 ± 0.5 | 0.9 ± 0.3 |
| PVR, WU | 5.1 ± 3.4 | 4.9 ± 4.1 | 4.8 ± 2.6 |
| SVR, WU | 19.4 ± 8.8 | 19.1 ± 8.0 | 22.1 ± 10. |
| Laboratory data | |||
| BNP (n = 63), pg/ml | 164 ± 140 | 308 ± 388 | 432 ± 316 |
| Outcome | |||
| Death | 10 (30) | 17 (36) | 5 (31) |
Values are mean ± SD or n (%).
*
Using Rich criteria (decrease in mPAP and PVR by ≥20%).
Abbreviations as in Table 2.