Table 2.
Comparison of Original RCT Sample with Current Sample
| Current CF-NBS N=13 |
Original CF-NBS N=77 |
Z-value | p-valuea | Current CF-SP N=26 |
Original CF-SP N=81 |
Z-value | p-valuea | |
|---|---|---|---|---|---|---|---|---|
| Female | 46.2% | 40.0% | 0.399 | 0.717 | 53.8% | 46.0% | 0.725 | 0.450 |
| White | 100% | 95.0% | 0.773 | 0.716 | 86.4% | 89.0% | −0.327 | 0.999 |
| Genotype: | ||||||||
| Homozygous F508del | 61.5% | 53.0% | −0.551 | 0.826 | 34.6% | 43.0% | 0.774 | 0.626 |
| Heterozygous F508del | 38.5% | 43.0% | 0.296 | 0.999 | 46.2% | 38.0% | −0.713 | 0.511 |
| Combine other and unknown | 0.0% | 4.0% | 0.723 | 0.770 | 19.2% | 18.5% | −0.081 | 0.954 |
| Pancreatic Status: | ||||||||
| Insufficiency | 92.3% | 79.0% | −1.11 | 0.296 | 65.4% | 58.0% | −0.666 | 0.526 |
| Sufficiency | 7.7% | 8.0% | 0.012 | 0.999 | 23.1% | 21.0% | −0.225 | 0.855 |
| Unknown | 0.0% | 13.0% | 1.37 | 0.185 | 11.5% | 21.0% | 1.07 | 0.325 |
RCT, randomized controlled trial; CF-NBS, cystic fibrosis-newborn screening group; CF-SP, cystic fibrosis-standard practice group