Table 1. TLR2 and TLR4 expression in association with chronic kidney diseases.
| TLR | Disease | Cell type |
|---|---|---|
| TLR2 | ESRD | Monocyte16 |
| Stage 3–4 CKD | Monocyte17 | |
| Obstructive hydronephrosis | Macrophage and myofibroblast20 | |
| IgA nephropathy | Macrophage and myofibroblast20 | |
| Type 1 DN | Endothelial cell and mesangial cell18; monocyte41; tubular cell44 | |
| UUO | Tubular cell20 | |
| TLR4 | ESRD | Neutrophil and monocyte16 |
| Type 2 DN | Proximal tubular cell19 | |
| Type 1 DN | Tubular cell20; monocyte41 |
Abbreviations: CKD, chronic kidney disease; DN, diabetic nephropathy; ESRD, end-stage renal disease; IgA, immunoglobulin A; TLR, Toll-like receptor; UUO, unilateral ureteral obstruction.