Figure 3. Closure of clean and contaminated wounds.

The areas of full-thickness wounds (initially 1 cm in diameter) were measured from the time of wounding until closure. A. All full-thickness aseptic wounds closed by day 25. Meth., methicillin; Vanc., vancomycin. B. Full-thickness wounds contaminated with microorganisms increased in size initially, while TP3 treated wounds did not exhibit the initial expansion and closed somewhat faster (day 25) than vancomycin-treated wounds. C. Photographs of representative wounds. “Fatal” indicates that no mice survived.