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. 2015 May 11;6(15):12955–12969. doi: 10.18632/oncotarget.4102

Table 2. Effect of TP3, methicillin and vancomycin on mice survival following intraperitoneal injection of 1×106 CFU of MRSA each mouse.

Strain and %Treatment % lethality Mean ± SD count (CFU/ml)
Blood Peritoneum Spleen Liver Mesenteric lymph nodes
MRSA
MRSA+PBS 20B 5.8×107±1.4×107B 1.x1010±3.6×109B 6.8×108±3.x108B 2.1×108±9.2×107B 5.4×107±2.6×107B
MRSA+Methcillin(0.01 mg/g) 20B 5.8×107±1.7×107B 4.9×109±2.2×109B 9.5×108±1.9×108B 3.7×108±8.1×107B 6.4×107±5.3×107B
MRSA+Vancomycin(0.01 mg/g) 0A 8×105±1.3×106B 2.7×109±1.5×109A 1.8×108±8.4×107B 1.7×108±3.8×107B 2×106±4.4×106A
MRSA+TP3(0.005 mg/g) 0A 0A 1.4×109±1×109A 9×107±8.2×107A 4.4×107±1×107A 1.6×106±1×106A

Lethality was monitored for 2 day following the injection of TP3 or antibiotic.