Table 3. Examples of differentially expressed genes in small and large AAA with some connection to immunity.
Symbol | Name | Small AAA | Large AAA | ||
---|---|---|---|---|---|
Fold change | Corrected P value | Fold change | Corrected P value | ||
IL1B | interleukin 1, beta | 5.08 | 0.002 | 3.85 | 0.001 |
IL6 | interleukin 6 | 6.28 | 0.004 | 6.48 | 0.002 |
IL8 | interleukin 8 | 4.49 | 0.005 | 3.65 | 0.004 |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.35 | 0.004 | 2.73 | 0.005 |
CXCL13 | chemokine (C-X-C motif) ligand 13 | 2.21 | 0.013 | 3.09 | 0.002 |
CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 3.14 | 0.039 | 2.59 | 0.041 |
CCL4L2 | chemokine (C-C motif) ligand 4-like 2 | 2.48 | 0.021 | 2.12 | 0.023 |
CD69 | CD69 molecule | 2.67 | 0.039 | 3.45 | 0.004 |
CD19 | CD19 antigen | 2.79 | 0.026 | 4.45 | 0.002 |
NKTR | natural killer-tumor recognition sequence | 2.37 | 0.002 | 2.66 | 0.001 |
CTLA4 | cytotoxic T-lymphocyte-associated protein 4 | 2.01 | 0.018 | - | - |
CD8A | CD8 antigen, alpha chain | - | - | 2.24 | 0.012 |
CD79A | CD79A antigen, immunoglobulin-associated alpha | - | - | 2.76 | 0.005 |
CD79B | CD79b molecule, immunoglobulin-associated beta | - | - | 3.43 | 0.004 |
FCRL2 | Fc receptor-like 2 | - | - | 2.53 | 0.002 |
FCRL5 | Fc receptor-like 5 | - | - | 2.01 | 0.001 |
FCRLA | Fc receptor-like A | - | - | 3.15 | 0.009 |
AAA, abdominal aortic aneurysm. Differentially expressed genes were determined by comparison of patients with small or large AAA with patients without AAA (Controls), (> 2-fold change, P value < 0.05 calculated with non-parametric Mann-Whitney test and corrected by Benjamini and Hochberg method).