Table 5. Examples of differentially expressed genes in AOD.
| Symbol | Name | Function | Fold change | Corrected P value |
|---|---|---|---|---|
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3 | Complex I | 2.71 | 0.003 |
| NDUFB3 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3 | Complex I | 2.53 | 0.003 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 | Complex I | 2.12 | 0.003 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6 | Complex I | 2.68 | 0.003 |
| SDHA | succinate dehydrogenase complex, subunit A | Complex II | 2.00 | 0.003 |
| SDHD | succinate dehydrogenase complex, subunit D | Complex II | 2.66 | 0.003 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | Comples III | 2.89 | 0.003 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | Comples III | 10.76 | 0.003 |
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | Comples III | 2.62 | 0.003 |
| COX5B | cytochrome c oxidase subunit Vb | Complex IV | 4.62 | 0.003 |
| COX6A1 | cytochrome c oxidase subunit VIa polypeptide 1 | Complex IV | 2.06 | 0.008 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 | Complex IV | 10.45 | 0.003 |
| COX6C | cytochrome c oxidase subunit VIc | Complex IV | 3.34 | 0.003 |
| COX7C | cytochrome c oxidase subunit VIIc | Complex V | 4.32 | 0.003 |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | Complex V | 2.22 | 0.003 |
| ATP5D | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | Complex V | 2.00 | 0.005 |
| ATP5J | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | Complex V | 3.13 | 0.003 |
| UCP2 | uncoupling protein 2 | Uncoupling | −3.73 | 0.014 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 | G/F/P | 2.84 | 0.008 |
| ALDH2 | aldehyde dehydrogenase 2 family | G/F/P | 2.03 | 0.017 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | G/F/P | 2.45 | 0.003 |
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | G/F/P | 2.61 | 0.003 |
| PDHB | pyruvate dehydrogenase beta | G | 2.64 | 0.003 |
| TPI1 | triosephosphate isomerase 1 | G | 2.23 | 0.003 |
| ACADL | acyl-CoA dehydrogenase, long chain | F | 2.04 | 0.003 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | F | 3.81 | 0.003 |
| MCEE | methylmalonyl CoA epimerase | P | 2.34 | 0.003 |
| MUT | methylmalonyl CoA mutase | P | 2.08 | 0.003 |
| C1S | complement component 1, s subcomponent | Complement | 2.08 | 0.044 |
| CD46 | CD46 molecule | Complement | 2.00 | 0.004 |
| CFH | complement factor H | Complement | 2.81 | 0.006 |
| CFI | complement factor I | Complement | 2.02 | 0.004 |
| C1QBP | complement component 1, q subcomponent binding protein | Complement | 2.10 | 0.003 |
| C1RL | complement component 1, r subcomponent-like | Complement | 2.08 | 0.003 |
| C7 | complement component 7 | Complement | 3.46 | 0.037 |
G, Glycolysis/Gluconeogenesis; F, Fatty acid metabolism; P, Propanoate metabolism; Complex I –V, mitochondrial complexes. Differentially expressed genes were determined by comparisons of patients of aortic occlusive disease (AOD) with patients without AAA (Controls), (> 2-fold change, corrected P value < 0.05 calculated with non-parametric Mann-Whitney test and corrected by Benjamini and Hochberg method.