Table 2. Incidence of renal tumor, tumor weight, invasion and metastasis in orthotopic xenografts.
| Group | No. of mice | Tumor incidence(%) | Tumor weight(mg) (mean ± SEM) | Beyond renal fascia rate(%) | Metastasis rate (%) |
|---|---|---|---|---|---|
| miR-1 | 6 | 6/6(100) | 136.7±39.2 | 6/6(100) | 3/6(50) |
| miR-NC | 6 | 6/6(100) | 49.3±21.2 | 1/6(16.7) | 0/6(0) |
| P-value | NSa | 0.000727b | 0.015c | 0.182c |
a
Not significant
b
Tumor weight was calculated by subtracting the weight of the right kidney (normal) from the weight of the left kidney (implanted with tumor).
c
P values were determined by Fisher's exact test.