Skip to main content
. 2015 Mar 26;6(15):13255–13268. doi: 10.18632/oncotarget.3658

Figure 2. Ovarian spheroids are highly resistant to cisplatin.

Figure 2

(A) The protein levels of endogenous genes for stem cell and EMT regulation in nine ovarian cancer cell lines were surveyed. (B, C) The ALDH1 activity (B) and spheroid formation (C) of the cell lines were determined. (D) Cell viability after treatment with cisplatin was compared between spheroids and parental cells. Spheroids and parental cells were treated with increasing doses of cisplatin (2.5–10 μM) for 48 h, and the viability of these cells was assessed. Data are presented as the mean ± SD of triplicate experiments.