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. 2015 Apr 15;6(15):13416–13433. doi: 10.18632/oncotarget.3826

Figure 1. Effects of PPARβ/δ ligands on the morphology of human MDMs and ovarian carcinoma TAMs.

Figure 1

A. Expression of the macrophage polarization marker genes CD163 and MMP9 in cultured TAMs and MDMs. The data were obtained by RT-qPCR analysis of TAMs (red data points; n = 4) and MDMs (blue: n = 11) from different donors. Horizontal lines show the medians; asterisks indicate statistical significance. B, C. Giemsa staining of human MDMs differentiated in XV0 medium for 8 days in the presence of the PPARβ/δ agonist L165,041 or solvent (DMSO). D, E. TAMs treated with agonist or DMSO as in panel B and C.