Table 2. Relation between sCD27 levels or CD70 expression and clinico-pathological features.
Data about CD70 expression was available for 49 patients, except for information about tumour-infiltrating lymphocytes which was only available for 42 patients
| sCD27 levels | CD70 expression | |||||
|---|---|---|---|---|---|---|
| Positive | Negative | p-value | Positive | Negative | p-value | |
| Gender | ||||||
| Male | 3 (20%) | 12 (80%) | 1.000 | 6 (18%) | 28 (82%) | 1.000 |
| Female | 1 (25%) | 3 (75%) | 2 (13%) | 13 (87%) | ||
| Smoking habit | ||||||
| No smoker | 1 (33%) | 2 (67%) | 0.576 | 3 (27%) | 8 (73%) | 0.536 |
| Smoker | 3 (23%) | 10 (77%) | 4 (13%) | 26 (87%) | ||
| Unknown | 0 (0%) | 3 (100%) | 1 (13%) | 7 (87%) | ||
| Histologic Type | ||||||
| Adenocarcinoma | 2 (20%) | 8 (80%) | 1.000 | 3 (9%) | 29 (91%) | 0.054 |
| Squamous | 2 (22%) | 7 (78%) | 4 (27%) | 11 (73%) | ||
| Large cell | NA | NA | 0 (0%) | 1 (100%) | ||
| Neuro-endocrine | NA | NA | 1 (100%) | 0 (0%) | ||
| Differentiation | ||||||
| Weak | 2 (40%) | 5 (60%) | 0.094 | 3 (23%) | 10 (77%) | 0.507 |
| Moderate | 0 (0%) | 8 (100%) | 4 (19%) | 17 (81%) | ||
| Strong | 0 (0%) | 1 (100%) | 1 (11%) | 8 (89%) | ||
| Unknown | 2 (33%) | 1 (67%) | 0 (0%) | 6 (100%) | ||
| TxNxMx | ||||||
| T1 | 0 (0%) | 2 (100%) | 0.790 | 3 (30%) | 7 (70%) | 0.096 |
| T2 | 2 (22%) | 7 (78%) | 3 (16%) | 16 (84%) | ||
| T3 | 2 (29%) | 5 (71%) | 0 (0%) | 15 (100%) | ||
| T4 | 0 (0%) | 1 (100%) | 2 (40%) | 3 (60%) | ||
| Lymph node | ||||||
| N0 | 2 (15%) | 11 (85%) | 0.090 | 6 (20%) | 24 (80%) | 0.645 |
| N1 | 2 (67%) | 1 (33%) | 2 (17%) | 10 (83%) | ||
| N2 | 0 (0%) | 3 (100%) | 0 (0%) | 5 (100%) | ||
| Unknown | NA | NA | 0 (0%) | 2 (100%) | ||
| Stage | ||||||
| I | 0 (0%) | 6 (100%) | 0.255 | 4 (29%) | 10 (71%) | 0.202 |
| II-IV | 4 (31%) | 9 (69%) | 4 (11%) | 31 (89%) | ||
| TIL | ||||||
| <10% | 0 (0%) | 6 (100%) | 0.622 | 1 (13%) | 7 (87%) | 0.557 |
| 10-50% | 0 (0%) | 1 (100%) | 5 (18%) | 23 (82%) | ||
| >50% | 4 (25%) | 12 (75%) | 0 (0%) | 6 (100%) | ||
| CD70+ TIL | ||||||
| <10% | 3 (60%) | 2 (40%) | 0.044 | 3 (12%) | 23 (88%) | 0.671 |
| 10-50% | 1 (8%) | 12 (92%) | 3 (20%) | 12 (80%) | ||
| >50% | 0 (0%) | 1 (100%) | 0 (0%) | 1 (100%) | ||
| CD27+ TIL | ||||||
| <10% | 2 (2%) | 0 (0%) | 0.012 | 0 (0%) | 4 (100%) | 0.499 |
| 10-50% | 2 (15%) | 11 (85%) | 0 (0%) | 4 (100%) | ||
| >50% | 0 (0%) | 4 (100%) | 6 (18%) | 28 (82%) | ||