Table 3. Correlations of PDL1 expression with immune-related parameters in IBC.
| Characteristics | N | IBC | P.value | |
|---|---|---|---|---|
| “PDL1-low” | “PDL1-high” | |||
| Lymphocyte infiltrate | 1.54E–03 | |||
| 0 | 9 | 8 (33%) | 1 (5%) | |
| 1 | 13 | 9 (38%) | 4 (20%) | |
| 2 | 11 | 6 (25%) | 5 (25%) | |
| 3 | 11 | 1 (4%) | 10 (50%) | |
| T-cell metagene | 1.16E–04 | |||
| High | 43 | 17 (24%) | 26 (62%) | |
| Low | 69 | 53 (76%) | 16 (38%) | |
| CD8+ T-cell metagene | 1.09E–02 | |||
| High | 34 | 15 (21%) | 19 (45%) | |
| Low | 78 | 55 (79%) | 23 (55%) | |
| B-cell metagene | 2.74E–06 | |||
| High | 45 | 16 (23%) | 29 (69%) | |
| Low | 67 | 54 (77%) | 13 (31%) | |
| LCK metagene | 5.11E–05 | |||
| High | 35 | 12 (17%) | 23 (55%) | |
| Low | 77 | 58 (83%) | 19 (45%) | |
| 28-kinase metagene | 2.96E–06 | |||
| High | 22 | 4 (6%) | 18 (43%) | |
| Low | 90 | 66 (94%) | 24 (57%) | |
| IFNα biological pathway | 6.06E–06 | |||
| Not activated | 52 | 44 (63%) | 8 (19%) | |
| Activated | 60 | 26 (37%) | 34 (81%) | |
| IFNγ biological pathway | 4.34E–09 | |||
| Not activated | 53 | 48 (69%) | 5 (12%) | |
| Activated | 59 | 22 (31%) | 37 (88%) | |
| TNFα biological pathway | 4.64E–09 | |||
| Not activated | 56 | 50 (71%) | 6 (14%) | |
| Activated | 56 | 20 (29%) | 36 (86%) | |