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. 2015 Apr 11;6(15):13506–13519. doi: 10.18632/oncotarget.3642

Table 4. Univariate and multivariate analysis for pathological response to neo-adjuvant chemotherapy in IBC.

Characteristics Univariate analysis Multivariate analysis
N OR [CI95] p-value N OR [CI95] p-value
Age, years > 50 vs. <=50 64 0.72 [0.29–1.72] 0.533
Histological type, other vs. ductal 64 0.38 [0.04–1.94] 0.392
Histological grade, 3 vs. 2 60 1.11 [0.42–3.05] 0.859
ER status, positive vs. negative 66 0.58 [0.24–1.37] 0.296
PR status, positive vs. negative 66 0.36 [0.14–0.86] 0.059 66 0.49 [0.17–1.38] 0.258
ERBB2 status, positive vs. negative 66 0.48 [0.15–1.3] 0.247
Molecular subtypes, ERBB2-enriched vs. basal 66 0.95 [0.28–3.18] 0.947
 Luminal A vs. basal 66 0.24 [0.05–0.94] 0.110
 Luminal B vs. basal 66 0.67 [0.16–2.55] 0.627
 Normal-like vs. basal 66 0.5 [0.12–1.81] 0.391
PDL1 group, high vs. Low 66 3.44 [1.42–8.63] 2.33E–02 66 3.49 [1.28–10.1] 4.46E–02
FAC/T response signature, “pCR-predicted” vs. “no pCR-predicted” 66 3 [1.22–7.54] 4.60E-02 66 1.58 [0.53–4.7] 0.487
Stromal signature, “pCR-predicted” vs. “no pCR-predicted” 66 2.86 [1.18–7.08] 0.052 66 3.28 [1.25–9.17] 0.047