Table 1. Changes of mRNA expression of mechanistic brain markers of PN4 mouse pups by triple antenatal DEX-treatments.

Postnatal day 4
Total brain–mRNA expression
Target	1x NaCl	1x DEXl	3x NaCl	3x DEX
Angiogenesis
VEGF-A	1.00 ± 0.13	0.97 ± 0.19	1 ± 0	0.48 ± 0.17 $
VEGFR2	1.00 ± 0.14	1.14 ± 0.33	1 ± 0	0.47 ± 0.13 $
Nrp1	1.00 ± 0.09	1.16 ± 0.23	1 ± 0	0.37 ± 0.12 $
Tie-2	1.00 ± 0.15	1.20 ± 0.40	1 ± 0	0.33 ± 0.09 $
Angpt1	1.00 ± 0.01	1.02 ± 0.17	1 ± 0	0.43 ± 0.17 $
Angpt2	1.00 ± 0.11	1.07 ± 0.22	1 ± 0	0.37 ± 0.16 $
Shh-pathway
Shh	1.00 ± 0.007	1.12 ± 0.20	1 ± 0	0.37 ± 0.17 $
PTCH1	1.00 ± 0.05	0.91 ± 0.12	1 ± 0	0.56 ± 0.25
Sox-18	1.00 ± 0.05	1.28 ± 0.20	1 ± 0	0.54 ± 0.13 $
Wnt-pathway
Axin-2	1.00 ± 0.003	0.94 ± 0.19	1 ± 0	0.45 ± 0.15 $
Brain endothelial cells–mRNA expression
Target	1x NaCl	1x DEXl	3x NaCl	3x DEX
Angiogenesis
VEGF-A	1.00 ± 0.09	2.20 ± 0.25 $	1 ± 0	0.61 ± 0.13 $
VEGFR2	1.00 ± 0.17	1.92 ± 0.57	1 ± 0	0.46 ± 0.13 $
Nrp1	1.00 ± 0.03	3.01 ± 0.27 $	1 ± 0	0.51 ± 0.12 $
Tie-2	1.00 ± 0.24	2.96 ± 0.39 $	1 ± 0	0.43 ± 0.13 $
Angpt1	1.00 ± 0.02	3.53 ± 0.64 $	1 ± 0	0.57 ± 0.13 $
Angpt2	1.00 ± 0.09	2.50 ± 0.50 $	1 ± 0	0.31 ± 0.07 $
Shh-pathway
Shh	1.00 ± 0.11	3.41 ± 0.32 $	1 ± 0	0.66 ± 0.19
PTCH1	1.00 ± 0.02	2.32 ± 0.13 $	1 ± 0	0.57 ± 0.13 $
Sox-18	1.00 ± 0.06	2.09 ± 0.24 $	1 ± 0	0.85 ± 0.36
Wnt-pathway
Axin-2	1.00 ± 0.05	1.99 ± 0.21 $	1 ± 0	0.54 ± 0.12 $

mRNA expression of mechanistic brain markers of PN4 mouse pups changed by triple antenatal DEX-treatments. Data are presented as the means ± SEM; n = 5–6 biological samples, at PN4 2–3 brains from one litter were pooled to one biological sample, biological samples were collected from at least three different litters

$: p<0.05 after two-tailed Student’s t-test.