Table 4.
Genome Wide Linkage (GWL) |
Genome Wide Association (GWA) |
||||||
---|---|---|---|---|---|---|---|
markerB | LODA | Populaton | Ref | dbSNP RS ID | Associated GeneB | P ValueC | Cytoband |
D4S2632 | 6.1 | utah | 45 | ||||
D4S3350 | 9.2 | rs16883786 | PCDH7 | 8.20×10−5 | 4p15.1 | ||
D4S2912 | 4.5 | Mexican Americans | 49 | ||||
D12S2070 | 2.98 | European American | 54 | rs206952 | MSI1 | 0.0001 | 12q24.31 |
D6S287 | 4.06 | French | 18 | rs11968468 | PLN | 0.0002 | 6q22.31 |
D17S949 | 3 | rs3809700 | ST6GALNAC2 | 7.22×10−5 | 17q25.1 | ||
D5S433 | 2.28 | French | 16 | rs10514384 | - | 0.0001 | 5q15 |
D10S587 | 2.9 | rs10885378 | VTI1A | 2.25×10−5 | 10q25.2 | ||
D19S418 | 3.59 | rs2544785 | RPL18 | 0.0004 | 19q13.32 | ||
D3S2427 | 3.3 | White American | 46 | rs9833131 | EPHB3 | 0.001 | 3q27.1 |
D3S1764 | 3.45 | Black American | rs2369949 | ACAD11 | 0.0003 | 3q22.1 | |
D3S1259 | White American | rs4680792 | RBMS3 | 0.003 | 3p24.1 | ||
D7S3051 | rs2711028 | OSBPL3 | 0.0001 | 7p15.2 | |||
D7S2847 | >2 | 53 | rs42172 | PIK3CG | 0.007 | 7q22.3 | |
D14S617 | Japan, China | rs4344663 | C14orf118 | 0.0003 | 14q24.3 | ||
GATA67G11 | rs13337356 | - | 0.003 | 16q12.2 | |||
D17S947 | rs2273026 | SHMT1 | 0.002 | 17p11.2 | |||
D7S817 | 3.8 | Nigeria, Yoruba | 20 | rs7798775 | HECW1 | 0.0001 | 7p14.1 |
D11S2000 | 3.3 | rs7945321 | TRPC6 | 8.05×10−5 | 11q22.1 | ||
D7S1804 | 3.2 | White American | 52 | rs125095 | PLXNA4B | 0.001 | 7q32.3 |
D13S257 | 3.2 | rs4942014 | ELF1 | 0.001 | 13q14.11 | ||
D2S1788 | 3.08 | rs848641 | FEZ2 | 0.0008 | 2p22.2 | ||
D7S3056-D7S2477 | 2.53 | White | 51 | rs10951131 | CARD11 | 6.81×10−5 | 7p22.2 |
D12S1052-D12S1064 | 3.41 | rs17110690 | TPH2 | 0.0002 | 12q21.1 | ||
D4S1647 | 2.63 | rs2567397 | PPP3CA | 0.009 | 4q23 | ||
GATA8B01 | 2.56 | African American | 50 | rs10958163 | LOC138046 | 0.0003 | 8q21.13 |
D10S212 | 2.06 | rs1917847 | C10orf120 | 6.10×10−5 | 10q26.13 | ||
D12PAH | 2.6 | rs7953150 | PTPN11 | 0.003 | 12q24.13 | ||
D7S2557 | 2.9 | White American | 47 | rs2529754 | SP8 | 0.0005 | 7p15.3 |
D7S484 | 2.4 | rs6463435 | - | 7.29×10−5 | 7p12.3 | ||
D5S1505 | 2.2 | rs17141793 | - | 0.0003 | 5q23.1 | ||
D2S347 | 4.04 | European American | 10 | rs3931840 | RALB | 0.0005 | 2q14.2 |
D5S1725-D5S1462 | 2.4 | rs423449 | AP3B1 | 2.95×10−5 | 5q14.1 | ||
D8S556-D8S592 | 2 | White American | 48 | rs4147527 | SAMD12 | 0.0003 | 8q24.12 |
D10S1435-D10S189 | 2.3–2.7 | rs10904363 | AKR1CL2 | 3.24×10−6 | 10p15.1 | ||
D14S283-D14S742-D14S1280 | 2.2–2.4 | rs1188538 | OR11G2 | 0.0009 | 14q11.2 | ||
SE30 | 2.13 | Dutch | 17 | rs6917225 | LYRM4 | 0.0002 | 6p25.1 |
D7S3056-D7S2477 | 2.4 | rs12055909 | FERD3L | 0.0004 | 7p21.1 | ||
- | 2.23 | Chinese | 55 | rs10952332 | GALNTL5 | 6.24×10−5 | 7q36.1 |
D13S265 | 2.09 | Samoans | 56 | rs9301947 | GPC6 | 0.001 | 13q31.3 |
AFMb035xb9 | 2.18 | European American | 57 | Rs9640008 | ZFAND2A | 0.0009 | 7p22.3 |
AAT013 | 2.03 | FAM44B | 0.001 | 5q35.2 |
Note.
Peak LOD scores >2.0 in previous GWLs.
‘-’ represents not available.
Our peak associaton signals in the corresponding regions identfied in GWLs.